Coumarins and derivatives
Apexbio Technology LLC 7-Amino-4-(trifluoromethyl)coumarin 53518-15-3 500mg
7-Amino-4-trifluoromethyl coumarin (CAS 53518-15-3) is a small-molecule antagonist targeting serotonin receptor subtype 1E (HTR1E) galanin receptor 2 (GALR2) and gamma receptor subtype 2 (GalR2) It is designed to antagonize these receptors thereby modulating receptor-mediated signaling pathways 7-Amino-4-trifluoromethyl coumarin exerts its biological activity primarily through receptor antagonism and inhibition of hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4) enzymatic activity In biochemical assays it demonstrates inhibitory activity toward HSD17B4 with reported bioactivity at approximately 21 M Based on these pharmacological properties 7-Amino-4-trifluoromethyl coumarin holds research potential in the investigation of protease activity receptor-mediated signaling and metabolic enzyme regulation
Selleck Chemical LLC Dicoumarol-50mg
Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.
Chem-Impex International, Inc. Esculin hydrate | 531-75-9 | MFCD00149492 | 25G
Esculin hydrate, 531-75-9, MFCD00149492, 25G
Cayman Chemical 7-AzIdo-4-methylcoumarIn 5mg
A fluorescent H2S probe; ex/em = 340/445 nm, respectively; selectively fluoresces in the presence of H2S over a panel of reactive nitrogen, oxygen, and sulfur species
Medchemexpress LLC HY-D0055 10mg Medchemexpress, 3-Cyano-7-ethoxycoumarin CAS:117620-77-6 Purity:>98%
Medchemexpress, HY-D0055 10mg 3-Cyano-7-ethoxycoumarin CAS:117620-77-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Ambeed 7-Amino-4-methylcoumarin | 26093-31-2 | MFCD00006868 | 1 g
7-Amino-4-methylcoumarin | Purity: 98% | Mol Wt: 175.18 | 26093-31-2 | MFCD00006868 | 1 g
Medchemexpress LLC 3-(1H-benzimidazol-2-yl)-7-(diethylamino)chromen-2-one | 27425-55-4 | MFCD00051348 | 99.8% | 333.38 g/mol | C20H19N3O2 | 100MG
Coumarin 7 (CAS 27425-55-4) is a coumarin-class laser dye and fluorescent research reagent used in spectroscopy and laser applications. It has molecular formula C20H19N3O2, a molecular weight of 333.38 g/mol, and is supplied with a reported purity of 99.80% for laboratory use.
- High reported purity: 99.8%.
- Suitable for spectroscopy, fluorescence, and laser dye studies.
- Molecular formula C20H19N3O2 and molecular weight 333.38 g/mol.
- Available in small research quantities, including 50 mg and 100 mg.
- Intended for research use in laboratory applications.
Chem-Impex International, Inc. 7-Amino-4-methylcoumarin | 26093-31-2 | MFCD00006868 | 1G
7-Amino-4-methylcoumarin, 26093-31-2, MFCD00006868, 1G
Sigma Aldrich Fine Chemicals Biosciences 3-(Bromoacetyl)coumarin 97% | 29310-88-1 | MFCD00488331 | 25G
3-(Bromoacetyl)coumarin 97% | Purity: 97% | Mol Wt: 267.08 | 29310-88-1 | MFCD00488331 | 25G
Medchemexpress LLC Coumarin 314 | 55804-66-5 | 250mg
Coumarin 314 is a dye which has an intense absorption in the visible and additionally presents a large solvent dependence[1]
Medchemexpress LLC Daphnetin (7,8-dihydroxycoumarin) | 486-35-1 | 99.8% | 178.14 | 5 MG
Daphnetin (7,8-dihydroxycoumarin) is a coumarin derivative found in plants of the Genus Daphne. It is a potent, orally active protein kinase inhibitor.
- Has IC50s of 7.67 μM, 9.33 μM, and 25.01 μM for EGFR, PKA, and PKC in vitro, respectively.
- Triggers ROS-induced cell apoptosis.
- Induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway.
- Possesses anti-inflammatory activity, inhibiting TNF-α, IL-1β, ROS, and MDA production.
- Exhibits schizontocidal activity against malaria parasites.
- Can be utilized in research for rheumatoid arthritis, cancer, and anti-malarial purposes.
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 1G
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 1G
4-Methylumbelliferyl acetate, 99%, Thermo Scientific™
CAS: 5-9-2747 ChEBI: CHEBI:17763
MP Biomedicals, Inc 7-Ethoxycoumarin, MP Biomedicals™
CAS: 31005-02-4 Molecular Formula: C11H10O3 Molecular Weight (g/mol): 190.198 MDL Number: MFCD00006877 InChI Key: LIFAQMGORKPVDH-UHFFFAOYSA-N Synonym: 7-ethoxycoumarin,7-ethoxy-2h-chromen-2-one,ethylumbelliferone,2h-1-benzopyran-2-one, 7-ethoxy,7-ethoxy-2h-1-benzopyran-2-one,7-ethoxycoumarine,pubchem8680,coumarin, 7-ethoxy,acmc-209hjx PubChem CID: 35703 ChEBI: CHEBI:28184 IUPAC Name: 7-ethoxychromen-2-one SMILES: CCOC1=CC2=C(C=C1)C=CC(=O)O2
4-Bromomethyl-6,7-dimethoxycoumarin 95%, Thermo Scientific™
CAS: 88404-25-5 Molecular Formula: C12H11BrO4 Molecular Weight (g/mol): 299.12 InChI Key: JGODLBJJCNQFII-UHFFFAOYSA-N Synonym: 4-bromomethyl-6,7-dimethoxycoumarin,4-bromomethyl-6,7-dimethoxy-2h-chromen-2-one,4-bromomethyl-6,7-dimethoxychromen-2-one,2h-1-benzopyran-2-one, 4-bromomethyl-6,7-dimethoxy,4-bromomethyl-6,7-dimethoxy coumarin,4-bdmc,brdmc-4,6,7,4-bromomethyl-6,7-dimethoxy-2-oxo-2h-benzopyran PubChem CID: 128870 IUPAC Name: 4-(bromomethyl)-6,7-dimethoxychromen-2-one SMILES: COC1=C(C=C2C(=C1)C(=CC(=O)O2)CBr)OC